GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aqp1 | increases expression | ISO | AQP1 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of AQP1 mRNA; cobaltous chloride results in increased expression of AQP1 protein | PMID:22415096 | Aqp1 | multiple interactions | ISO | Aqp1 (Rattus norvegicus) | 6480464 | CTD | [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [cobaltous chloride results in increased expression of EPAS1 protein] | PMID:23545307 | Aqp1 | multiple interactions | ISO | AQP1 (Homo sapiens) | 6480464 | CTD | calphostin C inhibits the reaction [cobaltous chloride results in increased expression of AQP1 protein]; Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA]; Dactinomycin inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA]; SB 203580 inhibits the reaction [cobaltous chloride results in increased expression of AQP1 protein]; Verapamil inhibits the reaction [cobaltous chloride results in increased expression of AQP1 protein] | PMID:22415096 | | ||||||||||||||||||||||
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