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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:34914
Term: phenolphthalein
Definition: A phenol that has formula C20H14O4.
Chemical ID: MESH:D020113
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1affects bindingISOESR1 (Homo sapiens)6480464CTDPhenolphthalein binds to ESR1 proteinPMID:12598185
Esr1increases activityISOESR1 (Homo sapiens)6480464CTDPhenolphthalein results in increased activity of ESR1 proteinPMID:25012808
Esr1multiple interactionsISOESR1 (Homo sapiens)6480464CTDPhenolphthalein binds to and results in decreased activity of ESR1 proteinPMID:25012808
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