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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2476 Species: Rattus norvegicus RGD Object: Gene Symbol: Cyp2f4 Name: cytochrome P450, family 2, subfamily f, polypeptide 4

Acc ID: CHEBI:34873 Term: N-nitrosodiethylamine Definition: A nitrosamine that has formula C4H10N2O. CasRN: 55-18-5 Chemical ID: MESH:D004052

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2F2 mRNA	PMID:18544905
multiple interactions	EXP		6480464	CTD	[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA	PMID:18253720