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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313526
Species: Mus musculus
RGD Object: Gene
Symbol: Mki67
Name: antigen identified by monoclonal antibody Ki 67
Acc ID: CHEBI:34568
Term: Benzo[ghi]perylene
Definition: An ortho- and peri-fused polycyclic arene that has formula C22H12.
Chemical ID: MESH:C006718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mki67decreases expressionISOMKI67 (Homo sapiens)6480464CTD1,12-benzoperylene results in decreased expression of MKI67 proteinPMID:35182551
Mki67increases expressionISOMKI67 (Homo sapiens)6480464CTD1,12-benzoperylene results in increased expression of MKI67 proteinPMID:31518672
Mki67multiple interactionsISOMKI67 (Homo sapiens)6480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in decreased expression of MKI67 protein]; Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of MKI67 protein]PMID:31518672 PMID:35182551
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