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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1597432
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lin28b
Name: lin-28 homolog B
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lin28bdecreases expressionISOLin28b (Mus musculus)6480464CTDbisphenol S results in decreased expression of LIN28B mRNAPMID:30951980
Lin28bincreases expressionISOLIN28B (Homo sapiens)6480464CTDbisphenol S results in increased expression of LIN28B mRNAPMID:34979203
Lin28bincreases methylationISOLin28b (Mus musculus)6480464CTDbisphenol S results in increased methylation of LIN28B promoterPMID:33297965
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