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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304662
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g12a
Name: phospholipase A2, group XIIA
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g12aincreases expressionISOPla2g12a (Mus musculus)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PLA2G12A mRNAPMID:20005886 PMID:21851831
Pla2g12amultiple interactionsISOPla2g12a (Mus musculus)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PLA2G12A mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G12A mRNA]; Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PLA2G12A mRNA]PMID:21851831 PMID:32352317
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