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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3539
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rasgrp1
Name: RAS guanyl releasing protein 1
Acc ID: CHEBI:33276
Term: delta-tocotrienol
Definition: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2.
Chemical ID: MESH:C082097
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rasgrp1increases expressionISORasgrp1 (Mus musculus)6480464CTDtocotrienol, delta results in increased expression of RASGRP1 mRNAPMID:22185406
Rasgrp1multiple interactionsISORasgrp1 (Mus musculus)6480464CTDtocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of RASGRP1 mRNA]PMID:22185406
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