GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdh1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CDH1 mRNA; bisphenol A results in decreased expression of CDH1 protein | PMID:25181051 PMID:29323181 PMID:30816183 PMID:34947998 | Cdh1 | affects methylation | ISO | Cdh1 (Mus musculus) | 6480464 | CTD | bisphenol A affects the methylation of CDH1 promoter | PMID:27334623 | Cdh1 | decreases expression | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of CDH1 mRNA; bisphenol A results in decreased expression of CDH1 protein | PMID:23391485 PMID:25690688 PMID:26363213 PMID:26407941 PMID:26546977 PMID:28808208 PMID:28844962 PMID:30611077 PMID:33024228 PMID:33419253 PMID:33469997 PMID:34743013 | Cdh1 | decreases expression | ISO | Cdh1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of CDH1 mRNA; bisphenol A results in decreased expression of CDH1 protein | PMID:26026914 PMID:26063408 PMID:27480627 | Cdh1 | increases expression | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | bisphenol A analog results in increased expression of CDH1 mRNA | PMID:32387340 | Cdh1 | increases expression | ISO | Cdh1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of CDH1 mRNA; bisphenol A results in increased expression of CDH1 protein | PMID:24769007 PMID:32156529 | Cdh1 | multiple interactions | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CDH1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in decreased expression of CDH1 protein; bisphenol A promotes the reaction [BRAF protein mutant form results in decreased expression of CDH1 protein]; FOXA1 protein affects the reaction [bisphenol A results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDH1 protein]; Genistein inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; plerixafor inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; Tamoxifen inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; U 0126 inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein] | PMID:25690688 PMID:26363213 PMID:26407941 PMID:28808208 PMID:28844962 PMID:31629898 PMID:33024228 PMID:33469997 PMID:34743013 | Cdh1 | multiple interactions | ISO | Cdh1 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of CDH1 protein; SNAI1 protein promotes the reaction [bisphenol A results in decreased expression of CDH1 protein] | PMID:27480627 PMID:37364641 | | ||||||||||||||||||||||
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