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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559469
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ror1
Name: receptor tyrosine kinase-like orphan receptor 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ror1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ROR1 mRNAPMID:25181051 PMID:34947998
Ror1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ROR1 genePMID:28505145
Ror1increases expressionISORor1 (Mus musculus)6480464CTDbisphenol A results in increased expression of ROR1 mRNAPMID:30951980
Ror1multiple interactionsISOROR1 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ROR1 mRNAPMID:28628672
Ror1multiple interactionsISORor1 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ROR1 mRNAPMID:30951980
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