GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nlrp3 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Dietary Fats] results in increased expression of NLRP3 protein; [Cholesterol co-treated with bisphenol A] results in increased expression of NLRP3 protein; bisphenol A promotes the reaction [Dietary Fats results in increased expression of NLRP3 mRNA]; NBN protein inhibits the reaction [[Cholesterol co-treated with bisphenol A] results in increased expression of NLRP3 protein]; Resveratrol inhibits the reaction [[Cholesterol co-treated with bisphenol A] results in increased expression of NLRP3 protein] | PMID:33239236 PMID:33265944 | Nlrp3 | decreases expression | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of NLRP3 mRNA | PMID:25181051 | Nlrp3 | increases expression | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of NLRP3 protein | PMID:35465754 | Nlrp3 | increases expression | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of NLRP3 mRNA; bisphenol A results in increased expression of NLRP3 protein | PMID:35439536 | Nlrp3 | multiple interactions | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | Fluvastatin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]; Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]]; taxifolin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]] | PMID:35465754 | Nlrp3 | multiple interactions | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA]; benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]; epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA]; epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of NLRP3 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of NLRP3 protein] | PMID:35439536 | | ||||||||||||||||||||||
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