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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308650
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sema5a
Name: semaphorin 5A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sema5aaffects expressionEXP 6480464CTDbisphenol A affects the expression of SEMA5A mRNAPMID:25181051
Sema5adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SEMA5A mRNAPMID:30816183 PMID:32528016 PMID:34947998
Sema5amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SEMA5A mRNAPMID:36041667
Sema5adecreases expressionISOSEMA5A (Homo sapiens)6480464CTDbisphenol A results in decreased expression of SEMA5A mRNAPMID:28591870 PMID:28711546
Sema5adecreases methylationISOSEMA5A (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of SEMA5A genePMID:31601247
Sema5aincreases expressionISOSema5a (Mus musculus)6480464CTDbisphenol A results in increased expression of SEMA5A mRNAPMID:30951980 PMID:35479511 PMID:35598803
Sema5amultiple interactionsISOSEMA5A (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of SEMA5A genePMID:31601247
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