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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318015
Species: Mus musculus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3increases expressionEXP 6480464CTDThioacetamide results in increased expression of NLRP3 proteinPMID:32721574
Nlrp3multiple interactionsEXP 6480464CTD3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Thioacetamide results in increased expression of NLRP3 protein]PMID:32721574
Nlrp3increases expressionISONlrp3 (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of NLRP3 mRNAPMID:34492290
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