GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esrra | increases expression | ISO | ESRRA (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased expression of ESRRA mRNA; fulvestrant results in increased expression of ESRRA protein | PMID:20211987 | Esrra | multiple interactions | ISO | ESRRA (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; AG 1879 inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESRRA mRNA]; Fulvestrant promotes the reaction [SP1 protein binds to ESRRA promoter]; Fulvestrant promotes the reaction [SP3 protein binds to ESRRA promoter]; GPER1 protein promotes the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; Pertussis Toxin inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA] | PMID:15968320 PMID:20211987 | |
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