GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adrb1 | increases expression | EXP | | 6480464 | CTD | Bisoprolol results in increased expression of ADRB1 mRNA | PMID:20668454 | Adrb1 | multiple interactions | EXP | | 6480464 | CTD | Bisoprolol binds to and results in decreased activity of ADRB1 protein | PMID:2897299 | Adrb1 | affects binding | ISO | ADRB1 (Homo sapiens) | 6480464 | CTD | Bisoprolol binds to ADRB1 protein | PMID:10372227 | Adrb1 | decreases activity | ISO | ADRB1 (Homo sapiens) | 6480464 | CTD | Bisoprolol results in decreased activity of ADRB1 protein | PMID:1389726 | Adrb1 | multiple interactions | ISO | ADRB1 (Homo sapiens) | 6480464 | CTD | [Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB1 protein; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB1 protein] | PMID:11562432 PMID:12535855 PMID:14730417 PMID:15060759 PMID:17200720 | | ||||||||||||||||||||||
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