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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:3090
Term: bicalutamide
Definition: A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.
Chemical ID: MESH:C053541
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1decreases expressionEXP 6480464CTDbicalutamide results in decreased expression of SLC2A1 proteinPMID:35151640
Slc2a1increases expressionEXP 6480464CTDbicalutamide results in increased expression of SLC2A1 proteinPMID:35151640
Slc2a1multiple interactionsEXP 6480464CTDbicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein]PMID:35151640
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