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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736474
Species: Homo sapiens
RGD Object: Gene
Symbol: G6PD
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:30808
Term: iron trichloride
Definition: An iron coordination entity that has formula Cl3Fe.
Chemical ID: MESH:C024555
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6PDdecreases activityISOG6pd (Rattus norvegicus)6480464CTDferric chloride results in decreased activity of G6PD proteinPMID:24599681
G6PDdecreases expressionISOG6pd (Rattus norvegicus)6480464CTDferric chloride results in decreased expression of G6PD mRNA; ferric chloride results in decreased expression of G6PD proteinPMID:24599681 PMID:30506659
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