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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732442
Species: Mus musculus
RGD Object: Gene
Symbol: Txn1
Name: thioredoxin 1
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txn1increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of TXN1 mRNAPMID:21715664 PMID:22228805
Txn1increases expressionISOTxn1 (Rattus norvegicus)6480464CTDBenzo(a)pyrene results in increased expression of TXN1 proteinPMID:16456883
Txn1increases expressionISOTXN (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of TXN mRNAPMID:21632981 PMID:31255691 PMID:32890658
Txn1multiple interactionsISOTxn1 (Rattus norvegicus)6480464CTDBenzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of TXN1 protein]; sodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of TXN1 protein]PMID:16456883
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