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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1342542
Species: Homo sapiens
RGD Object: Gene
Symbol: CST7
Name: cystatin F
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CST7affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of CST7 exonPMID:27901495
CST7increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CST7 mRNAPMID:20064835 PMID:22316170
CST7increases methylationEXP 6480464CTDBenzo(a)pyrene results in increased methylation of CST7 promoterPMID:27901495
CST7multiple interactionsISOCst7 (Mus musculus)6480464CTDBenzo(a)pyrene promotes the reaction [AHR protein binds to CST7 promoter]PMID:19654925
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