GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Coq8a | affects methylation | ISO | COQ8A (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of COQ8A 5' UTR | PMID:27901495 | Coq8a | decreases expression | ISO | COQ8A (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of COQ8A mRNA | PMID:32234424 | Coq8a | increases expression | ISO | Coq8a (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of COQ8A mRNA | PMID:20127859 PMID:22228805 | Coq8a | multiple interactions | ISO | Coq8a (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of COQ8A mRNA; AHR protein affects the reaction [Benzo(a)pyrene affects the expression of COQ8A mRNA] | PMID:22228805 PMID:27858113 | |
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