GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mir21 | increases expression | ISO | MIR21 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of MIR21 mRNA | PMID:26101800 PMID:27054085 PMID:27107786 | Mir21 | multiple interactions | ISO | MIR21 (Homo sapiens) | 6480464 | CTD | [sodium arsenite results in increased abundance of arsenite] which results in increased expression of MIR21 mRNA; IL6 protein affects the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of MIR21 mRNA]; IL6 protein promotes the reaction [sodium arsenite results in increased expression of MIR21 mRNA]; MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of MTOR protein]; MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of PTEN protein]; MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of BECN1 protein]; MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of MAP1LC3B protein]; MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]; MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]; MIR21 mRNA promotes the reaction [STAT3 protein promotes the reaction [sodium arsenite results in decreased expression of CDH1 protein]]; MIR21 mRNA promotes the reaction [STAT3 protein promotes the reaction [sodium arsenite results in increased expression of VIM protein]]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in decreased expression of MTOR protein]]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of BECN1 protein]]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased expression of MAP1LC3B protein]]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]]; PTEN protein affects the reaction [MIR21 mRNA affects the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]]; STAT3 protein affects the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of MIR21 mRNA]; STAT3 protein promotes the reaction [sodium arsenite results in increased expression of MIR21 mRNA] | PMID:24004609 PMID:26101800 PMID:27107786 | | ||||||||||||||||||||||
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