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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3044
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map2
Name: microtubule-associated protein 2
Acc ID: CHEBI:29474
Term: (S)-3,5-dihydroxyphenylglycine
Definition: A glycine derivative that is L-alpha-phenylglycine substituted at positions 3 and 5 on the phenyl ring by hydroxy groups.
Chemical ID: MESH:C079215
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2increases phosphorylationEXP 6480464CTD3,5-dihydroxyphenylglycine results in increased phosphorylation of MAP2 proteinPMID:15893642
Map2multiple interactionsEXP 6480464CTD[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased phosphorylation of MAP2 protein; Ammonia inhibits the reaction [3,5-dihydroxyphenylglycine results in increased phosphorylation of MAP2 protein]PMID:15893642
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