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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cldn11
Name: claudin 11
Acc ID: CHEBI:28909
Term: iprodione
Definition: An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide.
Chemical ID: MESH:C033148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cldn11increases expressionEXP 6480464CTDiprodione results in increased expression of CLDN11 proteinPMID:28576679
Cldn11multiple interactionsEXP 6480464CTD[carbendazim co-treated with iprodione] results in decreased expression of CLDN11 proteinPMID:28576679
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