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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:28838
Term: lutein
Definition: A carotenol that has formula C40H56O2.
Chemical ID: MESH:D014975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsEXP 6480464CTDLutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]PMID:34435724
Nfe2l2increases expressionISONfe2l2 (Mus musculus)6480464CTDLutein results in increased expression of NFE2L2 mRNA; Lutein results in increased expression of NFE2L2 proteinPMID:25815309 PMID:26187899
Nfe2l2multiple interactionsISONfe2l2 (Mus musculus)6480464CTDarsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein]; Lutein results in increased expression of and affects the localization of NFE2L2 proteinPMID:25815309 PMID:26187899
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