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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2915
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ins1
Name: insulin 1
Acc ID: CHEBI:28794
Term: coumarin
Definition: A chromenone having the keto group located at the 2-position.
Chemical ID: MESH:C030123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ins1multiple interactionsEXP 6480464CTDcoumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]PMID:19647726 PMID:21630391
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