GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nlrp3 | increases expression | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | Fructose results in increased expression of NLRP3 protein | PMID:22426011 PMID:24491314 | Nlrp3 | multiple interactions | ISO | Nlrp3 (Rattus norvegicus) | 6480464 | CTD | [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein]; [Dietary Fats co-treated with Fructose] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Fructose results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Fructose results in increased expression of NLRP3 protein]; Rutin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] | PMID:22426011 PMID:24491314 PMID:34939712 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |