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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731290
Species: Mus musculus
RGD Object: Gene
Symbol: Atp5pf
Name: ATP synthase peripheral stalk subunit F6
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp5pfdecreases expressionEXP 6480464CTDDoxorubicin results in decreased expression of ATP5PF mRNA; Doxorubicin results in decreased expression of ATP5PF proteinPMID:26873546
Atp5pfmultiple interactionsEXP 6480464CTD[Doxorubicin co-treated with Dexrazoxane] results in increased expression of ATP5PF mRNAPMID:26873546
Atp5pfdecreases expressionISOATP5PF (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of ATP5PF mRNAPMID:29803840
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