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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:28358
Term: rac-lactic acid
Definition: A racemate comprising equimolar amounts of (R)- and (S)-lactic acid.
Chemical ID: MESH:D019344
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDLactic Acid results in increased expression of CCND1 proteinPMID:36336208
Ccnd1multiple interactionsISOCCND1 (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [[Lactic Acid co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of CCND1 protein]; [Lactic Acid co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] results in increased expression of CCND1 protein; [Lactic Acid promotes the reaction [Cadmium Chloride results in increased abundance of Cadmium]] which results in increased expression of CCND1 protein; PKM protein affects the reaction [[Lactic Acid promotes the reaction [Cadmium Chloride results in increased abundance of Cadmium]] which results in increased expression of CCND1 protein]PMID:36336208
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