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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309856
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tbx18
Name: T-box transcription factor 18
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tbx18affects expressionISOTbx18 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of TBX18 mRNAPMID:24058054
Tbx18multiple interactionsISOTBX18 (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of TBX18 mRNAPMID:29704546
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