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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:28061
Term: alpha-D-galactose
Definition: D-Galactopyranose having alpha-configuration at the anomeric centre.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3increases expressionISODdit3 (Rattus norvegicus)6480464CTDGalactose results in increased expression of DDIT3 proteinPMID:34673010
Ddit3increases expressionISODDIT3 (Homo sapiens)6480464CTDGalactose results in increased expression of DDIT3 proteinPMID:23036742
Ddit3multiple interactionsISODdit3 (Rattus norvegicus)6480464CTDagomelatine inhibits the reaction [Galactose results in increased expression of DDIT3 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of DDIT3 protein]PMID:34673010
Ddit3multiple interactionsISODDIT3 (Homo sapiens)6480464CTD[Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein]; Phycocyanin inhibits the reaction [Galactose results in increased expression of DDIT3 protein]PMID:23036742 PMID:29427785
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