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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737547
Species: Mus musculus
RGD Object: Gene
Symbol: Cbr1
Name: carbonyl reductase 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cbr1multiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [titanium dioxide results in increased expression of CBR1 mRNA]PMID:31298478
Cbr1affects bindingISOCBR1 (Homo sapiens)6480464CTDCBR1 protein binds to resveratrolPMID:24064738
Cbr1multiple interactionsISOCBR1 (Homo sapiens)6480464CTD[resveratrol results in decreased activity of CBR1 protein] which affects the susceptibility to Doxorubicin; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of CBR1 mRNA]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of CBR1 protein]PMID:24064738 PMID:24975222
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