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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620289
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trim28
Name: tripartite motif-containing 28
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trim28increases phosphorylationISOTRIM28 (Homo sapiens)6480464CTDresveratrol results in increased phosphorylation of TRIM28 proteinPMID:24933654
Trim28multiple interactionsISOTRIM28 (Homo sapiens)6480464CTD2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TRIM28 protein]]; Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of TRIM28 protein]; resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TRIM28 protein]PMID:24933654
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