GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp17a1 | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of CYP17A1 mRNA | PMID:22719052 PMID:24524197 | Cyp17a1 | multiple interactions | EXP | | 6480464 | CTD | [[resveratrol analog co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [[resveratrol co-treated with CGA protein] results in decreased expression of CYP17A1 protein] which results in increased secretion of Progesterone; [resveratrol analog co-treated with CGA protein] results in decreased expression of CYP17A1 protein; [resveratrol co-treated with CGA protein] results in decreased expression of CYP17A1 protein; resveratrol promotes the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA]; Simvastatin promotes the reaction [resveratrol results in decreased expression of CYP17A1 mRNA] | PMID:19603415 PMID:24524197 | Cyp17a1 | decreases activity | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | resveratrol analog results in decreased activity of CYP17A1 protein; resveratrol results in decreased activity of CYP17A1 protein | PMID:24610083 | Cyp17a1 | decreases expression | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | resveratrol analog results in decreased expression of CYP17A1 mRNA; resveratrol results in decreased expression of CYP17A1 mRNA | PMID:24610083 PMID:24875446 | Cyp17a1 | multiple interactions | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | [Plant Extracts co-treated with Resveratrol] results in decreased expression of CYP17A1 mRNA | PMID:23557933 | |
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