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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346751
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2B6
Name: cytochrome P450 family 2 subfamily B member 6
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2B6increases expressionEXP 6480464CTDArsenic results in increased expression of CYP2B10 mRNAPMID:36720308
CYP2B6multiple interactionsEXP 6480464CTDNFE2L2 protein affects the reaction [Arsenic results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Arsenic results in increased expression of CYP2B10 mRNA]PMID:36720308
CYP2B6multiple interactionsISOCyp2b10 (Mus musculus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CYP2B10 mRNAPMID:32045263
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