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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc7a11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a11affects methylationISOSLC7A11 (Homo sapiens)6480464CTDArsenic affects the methylation of SLC7A11 genePMID:25304211 PMID:32603190
Slc7a11decreases expressionISOSlc7a11 (Mus musculus)6480464CTDArsenic results in decreased expression of SLC7A11 proteinPMID:37482551
Slc7a11increases expressionISOSLC7A11 (Homo sapiens)6480464CTDArsenic results in increased expression of SLC7A11 mRNAPMID:36720308
Slc7a11multiple interactionsISOSlc7a11 (Mus musculus)6480464CTD[Arsenic co-treated with Fluorides] results in decreased expression of SLC7A11 proteinPMID:37482551
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