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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2597
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fcer1a
Name: Fc epsilon receptor Ia
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fcer1amultiple interactionsISOFcer1a (Mus musculus)6480464CTDZinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]; Zinc promotes the reaction [FCER1A protein affects the localization of PRKCB protein]; Zinc promotes the reaction [FCER1A protein results in increased expression of IL6 mRNA]; Zinc promotes the reaction [FCER1A protein results in increased expression of IL6 protein]; Zinc promotes the reaction [FCER1A protein results in increased expression of TNF mRNA]; Zinc promotes the reaction [FCER1A protein results in increased expression of TNF protein]PMID:16818790
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