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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631369
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serpinf1
Name: serpin family F member 1
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpinf1decreases expressionISOSerpinf1 (Mus musculus)6480464CTDNicotine results in decreased expression of SERPINF1 mRNAPMID:21955143
Serpinf1decreases expressionISOSERPINF1 (Homo sapiens)6480464CTDNicotine results in decreased expression of SERPINF1 mRNA; Nicotine results in decreased expression of SERPINF1 proteinPMID:26536586
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