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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346235
Species: Homo sapiens
RGD Object: Gene
Symbol: NFATC1
Name: nuclear factor of activated T cells 1
Acc ID: CHEBI:18088
Term: formononetin
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
Chemical ID: MESH:C007768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFATC1multiple interactionsISONfatc1 (Mus musculus)6480464CTDformononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein]PMID:35315182
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