GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases activity | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Calcitriol results in increased activity of MAPK1 protein | PMID:19748465 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Calcitriol results in increased phosphorylation of MAPK1 protein | PMID:21803404 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | [CAMP results in increased activity of MAPK1] affects the reaction [Calcitriol results in increased expression of ATG5 mRNA]; [CAMP results in increased activity of MAPK1] affects the reaction [Calcitriol results in increased expression of BECN1 mRNA]; Calcitriol inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased phosphorylation of MAPK1 protein]; Calcitriol inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of HNF4A protein]; Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of RXRA protein]; Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]; Calcitriol results in increased phosphorylation of and results in increased activity of MAPK1 protein; CAMP mutant form inhibits the reaction [Calcitriol results in increased activity of MAPK1 protein]; MAPK1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]; RTKI cpd inhibits the reaction [Calcitriol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of HNF4A protein]]; U 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of RXRA protein]]; U 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]]; U 0126 inhibits the reaction [MAPK1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]] | PMID:12761878 PMID:15879110 PMID:19748465 PMID:20371703 PMID:36504884 | | ||||||||||||||||||||||
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