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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1increases expressionEXP 6480464CTDGlucose results in increased expression of SQSTM1 proteinPMID:30459625
Sqstm1multiple interactionsEXP 6480464CTDHU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]PMID:30459625
Sqstm1decreases expressionISOSQSTM1 (Homo sapiens)6480464CTDGlucose deficiency results in decreased expression of SQSTM1 proteinPMID:29649567
Sqstm1increases expressionISOSqstm1 (Rattus norvegicus)6480464CTDGlucose results in increased expression of SQSTM1 proteinPMID:28713934 PMID:29128638 PMID:35243728
Sqstm1increases expressionISOSQSTM1 (Homo sapiens)6480464CTDGlucose deficiency results in increased expression of SQSTM1 proteinPMID:34580807
Sqstm1multiple interactionsISOSqstm1 (Rattus norvegicus)6480464CTD3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]; Chloroquine promotes the reaction [Glucose results in increased expression of SQSTM1 protein]; Chloroquine promotes the reaction [Resveratrol promotes the reaction [Glucose results in increased expression of SQSTM1 protein]]; Inositol inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; Resveratrol promotes the reaction [Glucose results in increased expression of SQSTM1 protein]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]; ULK1 protein affects the reaction [Glucose results in increased expression of SQSTM1 protein]; ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]PMID:28713934 PMID:29128638 PMID:35243728
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