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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69032
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGES
Name: prostaglandin E synthase
Acc ID: CHEBI:17500
Term: 7alpha-hydroxycholesterol
Definition: The 7alpha-hydroxy derivative of cholesterol.
Chemical ID: MESH:C011724
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGESincreases expressionEXP 6480464CTDcholest-5-en-3 beta,7 alpha-diol results in increased expression of PTGES mRNAPMID:24802026
PTGESmultiple interactionsEXP 6480464CTDQuercetin analog inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased expression of PTGES mRNA]PMID:24802026
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