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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:17484
Term: benzyl isothiocyanate
Definition: An isothiocyanate that has formula C8H7NS.
Chemical ID: MESH:C031403
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases phosphorylationISOMAPK1 (Homo sapiens)6480464CTDbenzyl isothiocyanate results in increased phosphorylation of MAPK1 proteinPMID:31587482 PMID:33880814
Mapk1multiple interactionsISOMAPK1 (Homo sapiens)6480464CTDU 0126 inhibits the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK1 protein]; verlukast promotes the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK1 protein]PMID:31587482 PMID:33880814
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