GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il10 | increases expression | EXP | | 6480464 | CTD | Carbon Monoxide results in increased expression of IL10 protein | PMID:31732924 | Il10 | multiple interactions | EXP | | 6480464 | CTD | (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]; iodopravadoline inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]] | PMID:31732924 | Il10 | increases expression | ISO | Il10 (Mus musculus) | 6480464 | CTD | Carbon Monoxide results in increased expression of IL10 mRNA | PMID:21444764 | Il10 | multiple interactions | ISO | Il10 (Mus musculus) | 6480464 | CTD | Carbon Monoxide promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; HMOX1 protein affects the reaction [Carbon Monoxide results in increased secretion of IL10 protein] | PMID:21444764 | Il10 | multiple interactions | ISO | IL10 (Homo sapiens) | 6480464 | CTD | [Air Pollutants results in increased abundance of Carbon Monoxide] which affects the methylation of IL10 gene | PMID:33603036 | | ||||||||||||||||||||||
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