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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10073
Species: Homo sapiens
RGD Object: Gene
Symbol: ACP5
Name: acid phosphatase 5, tartrate resistant
Acc ID: CHEBI:17158
Term: methylglyoxal
Definition: A 2-oxo aldehyde derived from propanal.
Chemical ID: MESH:D011765
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACP5increases expressionISOAcp5 (Mus musculus)6480464CTDPyruvaldehyde results in increased expression of ACP5 mRNAPMID:31103701
ACP5increases expressionISOAcp5 (Rattus norvegicus)6480464CTDPyruvaldehyde results in increased expression of ACP5 mRNA; Pyruvaldehyde results in increased expression of ACP5 proteinPMID:31103701
ACP5multiple interactionsISOAcp5 (Mus musculus)6480464CTD[TNFSF11 protein co-treated with Pyruvaldehyde] affects the activity of ACP5 protein; [TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of ACP5 protein; bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of ACP5 protein]; MAPK8 protein affects the reaction [Pyruvaldehyde results in increased expression of ACP5 mRNA]PMID:30217477 PMID:31103701 PMID:31369791
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