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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aincreases expressionEXP 6480464CTDFormaldehyde results in increased expression of CDKN1A mRNAPMID:12679049
Cdkn1adecreases expressionISOCDKN1A (Homo sapiens)6480464CTDFormaldehyde results in decreased expression of CDKN1A mRNA; Formaldehyde results in decreased expression of CDKN1A proteinPMID:28937961 PMID:30236600
Cdkn1aincreases expressionISOCDKN1A (Homo sapiens)6480464CTDFormaldehyde results in increased expression of CDKN1A mRNA; Formaldehyde results in increased expression of CDKN1A proteinPMID:22525295 PMID:23649840
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