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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619565
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk14
Name: mitogen-activated protein kinase 14
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk14affects localizationISOMAPK14 (Homo sapiens)6480464CTDFormaldehyde affects the localization of MAPK14 proteinPMID:36534342
Mapk14increases expressionISOMapk14 (Rattus norvegicus)6480464CTDFormaldehyde results in increased expression of MAPK14 mRNAPMID:37263556
Mapk14increases phosphorylationISOMAPK14 (Homo sapiens)6480464CTDFormaldehyde results in increased phosphorylation of MAPK14 proteinPMID:15737199 PMID:36534342
Mapk14multiple interactionsISOMAPK14 (Homo sapiens)6480464CTDFormaldehyde affects the reaction [SET protein alternative form binds to MAPK14 protein modified form]; SET protein alternative form affects the reaction [Formaldehyde results in increased phosphorylation of MAPK14 protein]PMID:36534342
Mapk14multiple interactionsISOMapk14 (Rattus norvegicus)6480464CTDFAT1 mRNA alternative form promotes the reaction [Formaldehyde results in increased expression of MAPK14 protein]; Formaldehyde results in increased expression of and results in increased phosphorylation of MAPK14 proteinPMID:37263556
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