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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889 Species: Rattus norvegicus RGD Object: Gene Symbol: Rela Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Acc ID: CHEBI:16794 Term: scopolamine Definition: A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol. CasRN: 51-34-3 Chemical ID: MESH:D012601

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1551095	6480464	CTD	mangiferin inhibits the reaction [Scopolamine Hydrobromide results in increased phosphorylation of and results in increased activity of RELA protein]	PMID:19182383
multiple interactions	ISO	RGD:1551095	6480464	CTD	timosaponin AIII inhibits the reaction [Scopolamine Hydrobromide results in increased phosphorylation of and results in increased activity of RELA protein]	PMID:19426756
multiple interactions	ISO	RGD:1551095	6480464	CTD	Scopolamine Hydrobromide results in increased phosphorylation of and results in increased activity of RELA protein	PMID:19426756 PMID:19182383
multiple interactions	ISO	RGD:1551095	6480464	CTD	Scopolamine Hydrobromide results in increased phosphorylation of and results in increased activity of RELA protein	PMID:19182383 PMID:19426756