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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736474
Species: Homo sapiens
RGD Object: Gene
Symbol: G6PD
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:167162
Term: L-ascorbic acid 2-phosphate
Definition: An aldonolactone phosphate that is the 2-phosphate ester of L-ascorbic acid. It can stimulate collagen formation.
Chemical ID: MESH:C011669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6PDincreases activityISOG6pdx (Mus musculus)6480464CTDascorbate-2-phosphate results in increased activity of G6PD proteinPMID:19746226
G6PDincreases expressionISOG6pdx (Mus musculus)6480464CTDascorbate-2-phosphate results in increased expression of G6PD mRNAPMID:19746226
G6PDmultiple interactionsISOG6pdx (Mus musculus)6480464CTDDehydroepiandrosterone inhibits the reaction [ascorbate-2-phosphate results in increased activity of G6PD protein]PMID:19746226
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