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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:16708
Term: adenine
Definition: The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6.
Chemical ID: MESH:D000225
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1increases expressionEXP 6480464CTDAdenine results in increased expression of COL1A1 mRNA; Adenine results in increased expression of COL1A1 proteinPMID:34619300
Col1a1increases expressionISOCol1a1 (Rattus norvegicus)6480464CTDAdenine results in increased expression of COL1A1 mRNAPMID:25766432
Col1a1multiple interactionsISOCol1a1 (Rattus norvegicus)6480464CTDcamostat inhibits the reaction [Adenine results in increased expression of COL1A1 mRNA]PMID:25766432
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