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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2074
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ahr
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:16598
Term: DDE
Definition: A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
Chemical ID: MESH:D003633
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahraffects response to substanceISOAhr (Mus musculus)6480464CTDAHR protein affects the susceptibility to Dichlorodiphenyl DichloroethylenePMID:32721735
Ahraffects response to substanceISOAHR (Homo sapiens)6480464CTDAHR polymorphism affects the susceptibility to Dichlorodiphenyl DichloroethylenePMID:25084496
Ahrincreases expressionISOAhr (Mus musculus)6480464CTDDichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of AHR proteinPMID:32721735
Ahrincreases expressionISOAHR (Homo sapiens)6480464CTDDichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNAPMID:25316167
Ahrmultiple interactionsISOAHR (Homo sapiens)6480464CTDTNF protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA]PMID:25316167
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