GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of SQSTM1 mRNA; Lipopolysaccharides results in increased expression of SQSTM1 protein | PMID:34051206 PMID:35099110 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | 3-methyladenine inhibits the reaction [anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]]; [Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein; [Lipopolysaccharides co-treated with Uric Acid] results in increased expression of SQSTM1 protein; [stearic acid co-treated with Lipopolysaccharides] results in increased expression of SQSTM1 protein; anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; lycium barbarum polysaccharide inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 mRNA]; lycium barbarum polysaccharide inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein] | PMID:27611972 PMID:33810233 PMID:34051206 PMID:35099110 PMID:36796188 | Sqstm1 | increases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of SQSTM1 mRNA; Lipopolysaccharides results in increased expression of SQSTM1 protein | PMID:34464015 | Sqstm1 | multiple interactions | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of SQSTM1 mRNA; [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of SQSTM1 mRNA | PMID:35811015 PMID:35877022 | | ||||||||||||||||||||||
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